We still don't understand the cause of dilated cardiomyopathy, although research and treatment have advanced in the years since this patient was treated. Today there is greater interest in b-blockers for the treatment of congestive heart failure, and in immunological disease mechanisms, including apoptosis and cytokines such as tumour necrosis factor TNF-a.
Azzawi, M, Hasleton, P (1999) Tumour necrosis factor alpha and the cardiovascular system: its role in cardiac allograft rejection and heart disease CARDIOVASCULAR RESEARCH, 43(4), 850-859. [Health Sciences Library, no electronic copies]
Balke, CW, Shorofsky, SR (1998) Alterations in calcium handling in cardiac hypertrophy and heart failure CARDIOVASCULAR RESEARCH 37(2), 290-299. [Health Sciences Library, no electronic copies]
Bristow, MR (2000) beta-adrenergic receptor blockade in chronic heart failure CIRCULATION, 101(5), 558-569. [Health Sciences Library, click here for copies]
Brodde, OE, Michel, MC (1999) Adrenergic and muscarinic receptors in the human heart PHARMACOLOGICAL REVIEWS, 51(4), 651-689. [Health Sciences Library, click here for copies]
Carson, PE (1999) Beta blocker treatment in heart failure PROGRESS IN CARDIOVASCULAR DISEASES, 41(4), 301-321. [Health Sciences Library, no electronic copies]
Chien, KR (1999) Stress pathways and heart failure CELL 98(5), 555-558. [Health Sciences Library, no electronic copies]
deTombe, PP (1998) Altered contractile function in heart failure CARDIOVASCULAR RESEARCH 37(2), 367-380. [Health Sciences Library, no electronic copies]
Eichhorn, EJ (1998) Restoring function in failing hearts: The effects of beta blockers AMERICAN JOURNAL OF MEDICINE 104(2), 163-169. [Health Sciences Library, no electronic copies]
Elkayam, U, Karaalp, IS, Wani, OR, Tummala, P, Akhter, MW (1999) The role of organic nitrates in the treatment of heart failure PROGRESS IN CARDIOVASCULAR DISEASES, 41(4), 255-264. [Health Sciences Library, no electronic copies]
Feenstra, J, Grobbee, DE, Jonkman, FAM, Hoes, AW, Stricker, BHC (1998) Prevention of relapse in patients with congestive heart failure: the role of precipitating factors HEART 80(5), 432-436. [Health Sciences Library, click here for copies]
Hasenfuss, G (1998) Alterations of calcium-regulatory proteins in heart failure CARDIOVASCULAR RESEARCH 37(2), 279-289. [Health Sciences Library, no electronic copies]
Haunstetter, A, Izumo, S (2000) Future perspectives and potential implications of cardiac myocyte apoptosis CARDIOVASCULAR RESEARCH 45(3), 795-801. [Health Sciences Library, no electronic copies]
Hein, S, Kostin, S, Heling, A, Maeno, Y, Schaper, J (2000) The role of the cytoskeleton in heart failure CARDIOVASCULAR RESEARCH, 45(2), 273-278. [Health Sciences Library, no electronic copies]
Hunter, JJ, Chien, KR (1999) Mechanisms of disease: Signaling pathways for cardiac hypertrophy and failure NEW ENGLAND JOURNAL OF MEDICINE 341(17), 1276-1283. [Health Sciences Library, click here for copies] *** highly recommended *** get the password from the library!
Kojda, G, Kottenberg, K (1999) Regulation of basal myocardial function by NO CARDIOVASCULAR RESEARCH, 41(3), 514-523. [Health Sciences Library, no electronic copies]
Mahon, N, McKenna, WJ (1998) Calcium channel blockers in cardiac failure PROGRESS IN CARDIOVASCULAR DISEASES 41(3), 191-206. [Health Sciences Library, no electronic copies]
Meyer, M, Dillman, WH (1998) Sarcoplasmic reticulum Ca2+-ATPase overexpression by adenovirus mediated gene transfer and in transgenic mice CARDIOVASCULAR RESEARCH 37(2), 360-366. [Health Sciences Library, no electronic copies]
Movsesian, MA, Schwinger, RHG (1998) Calcium sequestration by the sarcoplasmic reticulum in heart failure CARDIOVASCULAR RESEARCH 37(2), 352-359. [Health Sciences Library, no electronic copies]
Paulus, WJ, Shah, AM (1999) NO and cardiac diastolic function CARDIOVASCULAR RESEARCH, 43(3), 595-606. [Health Sciences Library, no electronic copies]
Pepper, GS, Lee, RW (1999) Sympathetic activation in heart failure and its treatment with beta-blockade ARCHIVES OF INTERNAL MEDICINE 159(3), 225-234. [Health Sciences Library, click here for copies]
Phillips, RM, Narayan, P, Gomez, AM, Dilly, K, Jones, LR, Lederer, WJ, Altschuld, RA (1998) Sarcoplasmic reticulum in heart failure: central player or bystander? CARDIOVASCULAR RESEARCH 37(2), 346-351. [Health Sciences Library, no electronic copies]
Ravens, U, Dobrev, D (2000) Regulation of sarcoplasmic reticulum Ca2+-ATPase and phospholamban in the failing and nonfailing heart CARDIOVASCULAR RESEARCH, 45(1), 245-252. [Health Sciences Library, no electronic copies]
Richard, S, Leclercq, F, Lemaire, S, Piot, C, Nargeot, J (1998) Ca2+ currents in compensated hypertrophy and heart failure CARDIOVASCULAR RESEARCH 37(2), 300-311. [Health Sciences Library, no electronic copies]
Sabbah, HN (2000) Apoptotic cell death in heart failure CARDIOVASCULAR RESEARCH, 45(3), 704-712. [Health Sciences Library, no electronic copies]
Sack, MN, Smith, RM, Opie, LH (2000) Tumor necrosis factor in myocardial hypertrophy and ischaemia - an anti-apoptotic perspective CARDIOVASCULAR RESEARCH, 45(3), 688-695. [Health Sciences Library, no electronic copies]
Sander, GE, McKinnie, JJ, Greenberg, SS, Giles, TD (1999) Angiotensin-converting enzyme inhibitors and angiotensin II receptor antagonists in the treatment of heart failure caused by left ventricular systolic dysfunction PROGRESS IN CARDIOVASCULAR DISEASES, 41(4), 265-300. [Health Sciences Library, no electronic copies]
Schaub, MC, Hefti, MA, Zuellig, RA, Morano, I (1998) Modulation of contractility in human cardiac hypertrophy by myosin essential light chain isoforms CARDIOVASCULAR RESEARCH 37(2), 381-404. [Health Sciences Library, no electronic copies]
Singh, K, Communal, C, Sawyer, DB, Colucci, WS (2000) Adrenergic regulation of myocardial apoptosis CARDIOVASCULAR RESEARCH, 45(3), 713-719. [Health Sciences Library, no electronic copies]
Squire, IB, Barnett, DB (2000) The rational use of beta-adrenoceptor blockers in the treatment of heart failure. The changing face of an old therapy BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 49(1), 1-9. [Health Sciences Library, write down the details then click here for copies]
Wickenden, AD, Kaprielian, R, Kassiri, Z, Tsoporis, JN, Tsushima, R, Fishman, GI, Backx, PH (1998) The role of action potential prolongation and altered intracellular calcium handling in the pathogenesis of heart failure CARDIOVASCULAR RESEARCH 37(2), 312-323. [Health Sciences Library, no electronic copies]
Woodcock, EA, Matkovich, SJ, Binah, O (1998) Ins(1,4,5)P-3 and cardiac dysfunction CARDIOVASCULAR RESEARCH 40(2), 251-256. [Health Sciences Library, no electronic copies]