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- Chronic streptococcal infections are associated with two important
but fairly rare complications: glomerulonephritis and rheumatic
fever. These conditions result from the damaging effects of circulating
immune complexes.
- Streptococcus pyogenes produces an oxygen sensitive streptolysin
- streptolysin O. This causes haemolysis of red blood cells
and it is highly immunogenic. Patients who have had streptococcal
infections raise antibodies to streptolysin O.
- Mixing patient serum with streptolysin O will prevent it from
lysing red blood cells. By determining the anti-streptolysin
O (ASO) titre of a patient's serum one may determine if the
patient has had a streptococcal infection.
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Link to list of topics concerning upper respiratory tract
infections
Link to list of subjects
Page edited April 2006
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© John Heritage 2004, 2006
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