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Two species of the genus Candida, Candida albicans and Candida dubliniensis can form 'germ tubes' when incubated for up to two hours in serum. Above is a micrograph of a wet preparation of cells of Candida albicans incubated in horse serum for two hours. Typical yeast cells can be seen, together with elongated structures referred to as 'germ tubes'. Candia albicans is a common pathogen. As can be seen above it is also dimorphic, existing in a yeast phase and in a
mycelial form. Candida dubliniensis is a species that is associated with
oropharyngeal candidosis, particularly in AIDS patients. It is difficult to treat
using conventional first-line anti-candida therapy.
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