MB ChB Year 1: Nutrition and Energy

Lecture 4: Regulation

Dr Malcolm Hunter

Endocrine, paracrine and neurocrine secretion; criteria which should be met before a hormone can be assumed to be involved in regulation of the GIT in vivo; sites of synthesis and release of the major hormones gastrin, secretin, CCK-PZ GIP; the primary secretagogues of the major hormones and the actions of the hormones on the target tissues; the biochemical division of the hormones into the two families, gastrin-like and secretin-like hormones; the terminal amino acid sequence of gastrin and CCK-PZ which is responsible for the shared actions of these hormones; the distinction between the extrinsic and intrinsic nerve supplies to the GIT; the origins of the extrinsic nerves; the major effects of stimulation of the nerves on the GIT (e.g. motility, salivary, gastric and pancreatic secretions)

Dr Hunter's Powerpoint presentations are available on the VLE.

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