MB ChB Year 1: Nutrition and Energy

Sympathetic or parasympathetic stimulation; composition and cellular origin of the various components; the two-stage hypothesis of salivary secretion. the cellular basis of acid secretion; active K+/H+-exchange; the protective bicarbonate/mucus barrier mechanism; induction and prevention of ulceration; control of gastric acid secretion (cephalic, gastric and intestinal); components of pancreatic secretion (enzymes and electrolytes); reciprocal relationship between the concentrations of bicarbonate and chloride in pancreatic juice and flow rate-dependence; cephalic, gastric and intestinal phases of control; the life-cycle of enterocytes; c-AMP and secretory diarrhoea of cholera.

Dr Hunter's Powerpoint presentations are available on the VLE.

Gastrointestinal physiology 6th edn. by Leonard R. Johnson, Mosby, c2001

Physiology 5th edn. by Berne & Levy (Chapters 37, 38 & 39) Mosby, 2005

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